In addition to the physiological functions of protein-bound lipoic acid, there is increasing scientific and medical interest in potential therapeutic uses of pharmacological doses of free (unbound) lipoic acid (3)
Outdoor winter training, cold water access in lakes and rivers during spring and fall, and simply spending time in subzero temperatures activates similar physiological responses to dedicated cryotherapy chambers
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Zhong, Nanosuspension drug delivery system: preparation, characterization, postproduction processing, dosage form, and application, in Nanostructures for Drug Delivery, Elsevier, 2017, pp