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Severe pruritus that significantly impacts quality of life or sleep, or that does not respond to conservative measures
BMI of 30 or above, or BMI of 27 or above with an obesity-related health condition Health conditions such as high blood pressure, insulin resistance, sleep apnea, or elevated cholesterol History of unsuccessful attempts with diet, exercise, or commercial weight loss programs Willingness to combine medication with nutrition, movement, and lifestyle changes Not currently pregnant or planning pregnancy in the near term No contraindications to GLP-1 therapy based on health history and provider review Candidacy for compounded semaglutide and compounded tirzepatide is reviewed individually
Why This Phase Matters Momentum builds as habits feel more natural and sustainable
Whatever the timeline, consistent record-keeping from day one makes it far easier to interpret results at the end of a study and to compare outcomes against previously published GHRH and ghrelin-mimetic research
