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Figure 1 Figure 2 2 Apoptosis 2.1 Apoptotic signaling pathway Apoptosis, an RCD type that has been most widely investigated and precisely regulated, is featured by cell shrinking, plasma membrane blebbing, chromatin condensation, and apoptotic bodies formation (100)
The major contributing factors to such conditions are hormonal changes, friction generated by constrictive garments, shaving, waxing, and skin irritation
Lo Bello M, Nuccetelli M, Chiessi E, Lahm A, Mazzetti AP, Battistoni A, et al
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