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They constructed a quantitative model of intracellular GSH content using the probe ratio (B/Y)

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Handled the increased volume better than normal

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In heterodimeric GST complexes such as those formed by the cytosolic mu and alpha classes, however, the cleft between the two subunits is home to an additional high-affinity nonsubstrate xenobiotic binding site, which may account for the enzymes' ability to form heterodimers

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