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Remarkably, paternal alcohol use appears to interact with maternal exposures to accelerate these mitochondrial deficits, promoting a sustained pro-inflammatory state, which increases offspring susceptibility to liver disease and hepatocellular carcinoma ( Our ongoing research indicates that chronic paternal alcohol consumption impairs mitochondrial function within the male reproductive tract, correlating with alterations in sperm noncoding RNAs and long-lasting changes in offspring mitochondrial activity (Roach et al., 2023b)
Adv Neurotoxicol
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It puts retatrutide on a different efficacy plateau than the GLP-1 and dual-incretin agonists that have driven the obesity drug market for the last three years
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