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For example, Coriat et al
J Natl Cancer Inst
The main reason might be that high temperature seriously suppresses the activities of ribulose-1,5-bisphosphate carboxylase/oxygenase (Rubisco) large subunit (RBCL), Rubisco small subunit (RBCS) and other related enzymes 12 , and leads to impairment of chlorophyll biosynthesis 13
Further clinical trials are necessary to fully understand its safety, efficacy, and optimal dosing in humans
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