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This synthetic peptide has not been studied extensively as is classified as an investigational drug
The X-ray-derived data of small molecular fragments in complex with TGR used in this study to design the compounds here described are available in the PDB under accession codes 6FTC, 6FMU, 6FMZ, 6FP4, 2X99, 2X8G, 2X8H, 6ZST, 6ZP3, 6ZLP, 6ZLB, 7B02, 7NPX, 2V6O, 6RTJ, 6RTO, 6RTM, and 3H4K
So in patients for whom this matters, who may have heart disease, kidney disease, or obesity complications, then the benefits of GLP-1s do outweigh the potential risks, which are typically gastrointestinal side effects
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