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The per-dose amount stays at 100 mcg

According to NICE guideline NG28 , GLP-1 receptor agonists like Ozempic may be considered for adults with type 2 diabetes who have specific criteria, including a BMI of 35 kg/m or higher (adjusted for ethnicity) and specific problems associated with high weight, or a BMI lower than 35 kg/m where insulin would have significant occupational implications or weight loss would benefit other significant obesity-related comorbidities

Another reason may have less to do with semaglutide and more with whos taking it

Phase Weeks 1-26 Timing Daily Daily Dose 2 mg Notes Phase III trial exposure pattern