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Novo Nordisk A/S: Semaglutide 2.4 mg Demonstrates Superior Improvement in Both Liver Fibrosis and MASH Resolution in the ESSENCE Trial n.d

Four of the six genes investigated by quantitative RT-PCR were significantly up-regulated by Exendin-4 pre-conditioning, including Lactate dehydrogenase A ( Ldha ), Aldolase A ( Aldoa ), Phosphofructokinase ( Pfkp ) and Glucose-6-phosphate isomerase ( Gpi ) (Fig