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CD9 depletion synergized with ASCT2 inhibition to suppress PDAC organoid growth and prolong survival in KPC mice, highlighting the therapeutic potential of targeting the CD9ASCT2 axis

Serotonin syndrome: Combining MDMA with MAO inhibitors, SSRIs, lithium, or other serotonergic agents precipitates serotonin syndrome, a potentially fatal triad of hyperthermia, neuromuscular abnormalities, and altered mental status requiring emergency intervention

Triterpenoids CDDO and CDDO-Me down-regulate FLIP expression and sensitize AML cells to TRAIL-induced apoptosis