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In fact, discontinuing metformin may reduce the overall benefit of a combined regimen
GLP-1 Access, MariTide Data, and the Oprah Effect on Obesity Care This week on On The Pen , we break down a rare FDA walk-back on GLP-1 safety labeling, major pharma signals coming out of JPM 2026, and the growing tension between patient access and legislative efforts that could restrict compounding
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To date, the latter includes the GLP-1 RAs liraglutide and semaglutide, and the SGLT2 inhibitors empagliflozin and canagliflozin
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