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GLP-1 medications are best known for helping people manage diabetes and lose weight
Their core mechanism involves regulating the composition of gut microbiota to increase concentrations of SCFAs and secondary BAs, thereby activating ECCs to release 5-HT, enhancing ACh secretion from cholinergic neurons, and optimizing ENS inhibitory neural signals via the neuronal nNOS pathway, ultimately promoting gastric emptying and regulating intestinal transit rhythms (Huang et al., 2023
Both are secreted in the gut in response to food
About this article Cite this article Ambrosini, G., Cordani, M., Zarrabi, A
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