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Trace amine-associated receptor 1 (TAAR1) agonism as a new treatment strategy for schizophrenia and related disorders
at higher concentrations, these same compounds exhibit inhibitory or overtly toxic effects
Mitochondria cannot manufacture glutathione de novo , so glutathione is synthesized in the cytosol and a small fraction of the total cellular pool is then imported into the mitochondrial matrix by carrier-mediated transport (22
Therefore, iron chelators have been investigated as potential therapeutic agents to mitigate the iron-related neurotoxic conditions
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