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This is not merely additive: the MOTS-c may amplify or extend the mitochondrial biogenesis signal beyond what training alone achieves, particularly in older adults whose endogenous MOTS-c response to exercise is blunted [2]

MAPK signaling contributes to therapeutic resistance by enhancing the expression of drug efflux transporters such as MDR1 and P-gp and by upregulating antiapoptotic genes such as Bcl-2

To compare the frequency difference between groups, the chi-squared test or Fischers exact test was used

The report cited a 2020 survey finding that 61% to 100% of complications from cosmetic procedures that dermatologists addressed originated from procedures in medical spa settings