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After you eat, your gut releases GLP-1, which slows digestion and helps you feel full

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On average, semaglutide led to a placebo-corrected weight loss of about 12%, while tirzepatide reached an impressive 18% reduction in body weight

Patients in whom heart failure (HF) or chronic kidney disease (CKD) is prevalent, should receive a treatment intensification with an SGLT-2 inhibitor with the respective evidence from clinical studies due to the respective data (7072)