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Age-related changes in the global DNA methylation profile of leukocytes are linked to nutrition but are not associated with the MTHFR C677T genotype or to functional capacities

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However, insufficient research is currently available to support the role of lycopene in preventing malignant transformation of digestive lesions, thus, larger sample sizes of human clinical trials are warranted to further uncover the potential role of lycopene in preventing the malignant transformation of digestive lesions