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These structural changes not only create cosmetic concerns but can potentially impair drug absorption, leading to unpredictable glycemic control and suboptimal therapeutic outcomes

These ligands can be stably attached to the surface of exosomes through covalent bonds to enhance their targeting ability

The pyroptotic process is typically initiated by recognition of pathogens in the cytosol or endogenous danger signals via inflammasomes, which recruit and activate inflammatory caspases such as caspase-1, -4, -5, -11 (160, 161)