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NICE guidance (NG28) recommends GLP-1 receptor agonists in type 2 diabetes only for specific patients, typically when other treatments have proven insufficient and when certain BMI thresholds are met

This fall in liver fat is strongly associated with body weight loss, with close to maximal liver fat change occurring at approximately 20% total weight loss

HbA1c in participants with pre-existing pre-diabetes The adjusted mean HbA1c change in ITT participants with pre-diabetes at baseline in the semaglutide group ( n = 2) was 8.0 mmol mol 1 (s.e

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