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The dose of vitamin B12 injection for adults may vary depending on the problem to be treated: Treatment of mild nerve pain : the initial dose is 5,000 IU until pain resolves Treatment of intense nerve pain: the initial dose can be increased to 15,000 IU per day and reduced by the doctor as pain resolves Treatment of pernicious anemia: the dose can vary from 100 to 1000 IU per day and the treatment time varies from person to person
The 2024 NICE guideline NG239 sets out a more intensive loading schedule for patients with neurological involvement precisely because their starting point is worse
(Accessed 28th August 2024)
Claimed outcome NAD+ changes Evidence level Cell and animal evidence What research currently shows Blocking NNMT can preserve nicotinamide, a building block used to make NAD+
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