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The suspected mechanism is glucagon activity: the glucagon receptor is expressed in certain tissues of the peripheral nervous system, and its chronic activation appears to alter neurosensory signaling in some subjects
Most of the mutations in SLC22A5 are missenses mutations but nonsense, splice site, and deletion/insertion mutations have also been identified
This is not ideal as a permanent solution, whole foods matter, but it is a practical tool for hitting targets on days when eating feels like a chore
If you are unsure where to start or which nutrients your body needs most, using a tool like the Health Quiz can help you narrow down your options based on your specific health goals and lifestyle
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