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Wegovy's cost includes manufacturing standards tested across millions of doses, adverse event reporting systems, and post-market surveillance that compounded versions don't replicate

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GLP-1 increased cAMP but did not affect amylase secretion

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9 Approved in 2005, exenatide was the first GLP-1 drug to be made available, and later modifications allowed for its extended release

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Bicknell says an oral formulation of a protein is really exciting from a pharmacological perspective, as well as offering greater accessibility for patients

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