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Systemic inflammatory response syndrome (SIRS) following unregulated IV administration, presenting with fever above 41 degrees Celsius, acute liver injury, and clotting abnormalities, is also documented in a 2025 case report
While generally well-tolerated, allergic reactions to tirzepatide can occur, ranging from mild injection site reactions to serious systemic hypersensitivity including anaphylaxis and angioedema
The gut microbiome: Relationships with disease and opportunities for therapy
The majority of the cases have been reported in East Asia (234)
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