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Additionally, upon treatment with IL-1 or TNF-, endothelial cells can synthesize and secrete chemokines structurally similar to the neutrophil-activating factor (NAF) derived from human monocytes, further enhancing neutrophil activation and migration (111)
Continue holding the pen against your skin for the full time specified in the Instructions for Use (typically 5-10 seconds) to ensure the full dose is delivered
Contact your GP or diabetes specialist nurse if you have concerns about side effects, are unable to tolerate the medication, or experience any warning signs requiring medical attention
Wipe the red inner seal of the pen with one of the alcohol wipes
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