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In patients with hepatic encephalopathy, the impaired reaction of cerebral oxyhemoglobin concentration might occur due to astrocyte swelling and dysfunction 42,43,44 because some reports showed that astrocyte controls the regional cerebral blood flow and provides energy sources such as ketone body and carnitine to the neuron 39,41

29 These results suggests that the reported negative retinopathy outcomes observed in some studies may not be specific to the GLP-1/GIP agonists, but rather scenarios where their use resulted in larger drops in A1c

It shows therapeutic potential in models of myocardial infarction, liver injury, and even SARS-CoV-2 infection

In a study published by Rangsimawong, the effect of sonophoresis at a frequency of 20 kHz on the transdermal administration of sodium fluorescein (NaFI)using lipid-based nanocarriers including niosomes (NI), liposomes (LI), and solid lipid nanoparticles (SLN)