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Administer at once or at different times via nasal spray, alternating nostrils
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These mechanisms involve different steps which are currently not well-characterized: (1) entrance of Ca 2+ into the enterocytes through the Ca 2+ -selective transient receptor potential (TRP) channel TRPV6 and the voltage-gated calcium channel Cav1.3, a member of the L-type calcium channel family
These proposed mechanisms sound compelling, but it is vital to remember that these effects are mostly observed in rodent models or cell cultures, not in humans
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