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In human cartilage pellet cultures, GLP-1 analogues restored proteoglycan markers suppressed by IL-1

Other factors that could lead to B12 deficiency are: Lack of adequate production of the intrinsic factor needed for B12 absorption B12 deficiency is common in elderly people as absorption of the vitamin reduces with age People who have had any intestinal surgery, such as that for weight loss Those with gut conditions such as Crohn's Disease, inflammatory bowel disease, or celiac disease QUESTION See Answer Vitamin B12 injections Vitamin B12 supplements are given based on the condition that causes deficiency

These inflammation-associated hyperpigmented patches are of no clinical significance, their biological significance is unknown, and treatment is not required