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Many patients have become comfortable with the once-a-week injection schedule, which is more convenient than daily medication

Inconsistent dosing creates inconsistent side effects, which disrupts training schedules in ways that are difficult to plan around

Hepatotoxicity, Including Drug-Induced Liver Injury: Hepatotoxicity, including severe, life-threatening, and potentially fatal cases of drug-induced liver injury (DILI), has occurred in patients treated with Bruton tyrosine kinase inhibitors, including IMBRUVICA

Evaluate other medications that may affect heart rate or rhythm, including decongestants, stimulants, thyroid hormone replacement, or medications that prolong the QT interval