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DPP-4 inhibitors, such as sitagliptin, alogliptin, linagliptin and saxagliptin, were synthesized to prolong the half-life of GLP-1 (102)
They are not illegal to buy or own, but they are not approved for human use, so are not subject to the quality controls that govern pharmaceutical manufacturing
Many patients report experiencing noticeable changes within the first 4 to 8 weeks of using Tirzepatide, with more significant weight loss often visible after a few months of treatment
Lower concentrations allow for easier volume measurement when beginning therapy, while higher concentrations reduce injection volume as patients advance to maintenance doses
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