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Obesity The global incidence of obesity is steadily increasing and is closely linked to various health issues, including type 2 diabetes, atherosclerosis, hypertension, cardiovascular diseases, and cancer

Proposed mechanisms include inhibition of pro-inflammatory signalling (NF-B, MAPK), preservation of epithelial barrier integrity, modulation of gut microbiota and immunomodulation of both mucosal and systemic inflammation

Many of the vegetables that are rich in glutathione are also rich in sulfur, like kale, cauliflower, and brussel sprouts

Furthermore, ELISA detection showed that after GLP-1RA treatment, the levels of IL-6, IL-1, and TNF- in synovial tissue were significantly reduced (Fig