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Description

The measurement of excitatory neurotransmitter glutamate in vivo by 1 H MRS is straightforward due to its high cerebral concentration, on the contrary, the low level of GABA makes it challenging to be measured in vivo

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Therefore, the current evidence is more appropriately interpreted as suggesting a possible conception-window benefit after metabolic optimization, rather than confirming a reproducible treatment effect on hard reproductive outcomes (111, 112, 124)

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