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In the absence of 5MTHF, free Co(I)B12 can readily reacts with nitrous oxide to form NO-Co(III)B12, which is inactive, yet will clog up methylation by Methionine synthase, and irreversibly inactivate the enzyme, hence explaining the toxicity of Nitrous oxide
When to talk to your prescriber about adjustments Your dosage chart is a guide, not a prescription carved in stone
This malabsorption can stem from an autoimmune response, ushering in a scenario where the body mistakenly attacks its cells and tissues
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