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Curious whether you see upcoming agents (e.g., amylin combos, oral GLP-1s) meaningfully addressing this, or if this remains an open clinical and commercial challenge
Results: Abundant neutrophil accumulation and NETs formation were observed in NASH progression
However, under conditions of oxidative stress, superoxide radicals (O2) react with NO to form ONOO , reducing the bioavailability of NO and leading to endothelial dysfunction [67]
Many studies focus on the drugs ability to increase skin pigmentation but do not fully address long-term safety
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