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Participants receiving the highest dose (12 mg weekly) achieved a mean body weight reduction of approximately 24% over 48 weeks results that exceeded those seen with currently approved agents at the time of publication

This not only enhances patient compliance but also reduces the likelihood of side effects associated with more complex treatment regimens

119 When included as part of a low-saturated fat/low-cholesterol diet, they can lower LDL cholesterol, generally by roughly 510%, in hypercholesterolemic and diabetic patients, and may reduce LDL cholesterol in healthy individuals as well