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Huang J, Chen M, Whitley MJ, Kuo HC, Xu ES, Walens A, et al

Any of these conditions mean the current dose still has room to work, and increasing would likely produce side effects that offset any additional benefit

This can lead to complications such as fetal growth restriction, preterm birth and even stillbirth

Kraemer et al., 2020) and altering the expression of thousands of genes, many of which are involved in the regulation of skeletal muscle structure, fiber type (Dubois et al., 2013), and mRNA transcription (MacLean et al., 2008) (Figure 1)

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