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(2.2) The recommended starting dosage in patients with NYHA Class I or II congestive heart failure is 25 mg of alogliptin and 15 mg of pioglitazone (2.4) Prior to initiation, assess renal function with creatinine clearance (CrCl) (2.3) Mild renal impairment (creatinine clearance [CrCl] 60 mL/min): same as the recommended dosage in patients with normal renal function
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