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Clin Pharmacol (2022) 14:617
In typical PINK1-Parkin-mediated mitophagy, damaged mitochondria encapsulated in autophagosomes depend on key membrane fusion factors, including Rab7, small GTPase-driven homotypic fusion, and the HOPS (homotypic fusion and vacuole protein sorting) complex, for docking and fusion with lysosomes [136, 137]
doi: 10.1105/tpc.111.083998 20 HalliwellB.FoyerC
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