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GLP-1 receptor agonists, such as Wegovy, which contain the active ingredient semaglutide, are a class of medications widely used for obesity and type 2 diabetes
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Por lo tanto, en el contexto de la diabetes mellitus tipo 2 (DMT2), las terapias basadas en GLP-1 (7-36) se han desarrollado basndose en estrategias consistentes en incrementar la presencia de GLP-1 (7-36) en sangre, bien mediante compuestos inhibidores de la actividad del enzima DPP-4 (p
Since either metformin or GLP-1 analogue has vascular protective effects 7,24 , we reasonably hypothesized that this combination therapy might also have a synergistic protective effect on endothelial function
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