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B12 has a very low toxicity, so large amounts are not considered dangerous
Self-administered B12 shots are generally recommended for individuals: whose bloodwork has documented low B12 levels Patients with pernicious anemia or a lack of intrinsic factor Individuals with Crohn's disease, celiac disease, or post-bariatric surgery malabsorption Vegans and strict vegetarians are unable to correct the deficiency through diet Older adults whose stomach acid production has declined with age Anyone on long-term metformin or proton pump inhibitors Across most of the U.S., injectable B12 is not sold over the counter a clinician has to write the script before a pharmacy can dispense it
OTC B12 Supplement Options: 500 mcg tablets 1,000 mcg capsules 2,000 mcg sublingual drops Bioavailability Differences The way your body absorbs vitamin B12 varies between injections and oral supplements
Immune Reactivity: The FDA has previously flagged concerns that compounded peptides like BPC 157 carry risks of triggering unexpected immune or allergic reactions
