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Oral administration of myricetin significantly reduces Fe 2+ levels in the substantia nigra of PD rats, inhibits neuronal ferroptosis, decreases ROS production, downregulates malondialdehyde (MDA) and -synuclein (-Syn) expression, elevates GSH levels, and ameliorates motor deficits
Materials and methods Institutional Review Board approval was obtained at the University of Washington for this single-center study of 15 participants with mid-stage PD
