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In 1973, Engel and Angelini reported the first case of L-carnitine deficiency and treated it with carnitine
doi:10.5021/ad.24.043 7
In mammals, the tautomerization of dopachrome to DHICA (no decarboxylation), which is the basis of DHICA eumelanin, is also known
L-carnitine: physiological functions and active forms In physiological terms, carnitine acts as a shuttle ( carnitine shuttle ) to carry activated fatty acids into the mitochondrion, a necessary step to produce ATP when lipids predominate as fuel
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