However, as research continued, experts found that GHK could modulate a number of different cells besides those in the liver.4 GHK is naturally found in human saliva, plasma, and urine, but its standard levels are reduced by over half once you reach age 60
Indeed, Serotonin Synthesis Amplification has been pursued since the 1970s, using as the active compound either 5-hydroxytryptophan, 5 HTP (the natural rate-limiting serotonin precursor) (11) , tryptophan (5-HTP precursor) (28) , methyl-folate (amplifies 5-HTP synthesis) (29) , lithium (amplifies 5-HTP synthesis) (34) , or thyroid hormone (amplifies 5-HTP synthesis) (35)
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Hormonal alterations Since stress has been described as a potential trigger for ME/CFS (422) and cause of symptom flare-ups (423, 424), it is likely that the HPA axis- the neurobiological stress system- may be implicated in ME/CFS (53, 425, 426), as well as abnormalities in growth hormone (GH) secretion and dysfunctional adrenergic metabolism (255)