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What it had actually done was agree to pay $249 per month indefinitely, at federal scale, with no compounding alternative for drugs the market had demonstrated could be produced and distributed profitably at half that price, in exchange for regulatory favors that compressed the manufacturers product timelines by nearly a year and opened a federally subsidized acquisition channel for the next generation of their pipelines

doi:10.1002/14651858.CD004052.pub2

Once-weekly formulations (semaglutide, dulaglutide) can be injected morning or night on the same day each week, whilst twice-daily exenatide must be given within 60 minutes before main meals