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Are there specific dosing requirements for patients with certain medical conditions

Oral Absorption vs

In contrast, the passive diffusion process of B 12 absorption normally a very small portion of total absorption of the vitamin from food consumption may exceed the haptocorrin- and IF-mediated absorption when oral doses of B 12 are very large, with roughly 1% efficiency

Fermented foods (such as tempeh), nori, spirulina, chlorella algae, and unfortified nutritional yeast cannot be relied upon as adequate or practical sources of B-12.39,40 Vegans must regularly consume reliable sourcesmeaning B-12 fortified foods or B-12 containing supplementsor they could become deficient, as shown in case studies of vegan infants, children, and adults