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69,1 mmol/mol) or very high cardiovascular risk, and the regimen should include an SGLT-2 inhibitor and/or a GLP-1 receptor agonist ( 1c 1.52.0% above target, especially when therapies with high glycemic efficacy and proven cardiovascular or renal benefit are indicated ( 1c (11.6%, 102.6 mmol/mol), BMI 32.6 kg/m 2 , hypertension, proteinuria, fulfilling criteria for early combination therapy under both sets of guidelines

Boehringer Ingelheim / Zealand Pharma (ZLDPF): Survodutide (aka BI 456906) [44] [44] In a placebo-controlled study evaluating the GLP1R/GR dual agonist (Obesity Indication), patients received weekly subcutaneous injections of 4.8mg for a duration of 46 weeks

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