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Nanotechnology is poised to revolutionize delivery, with ROS-responsive nanoparticles encapsulating antioxidants (e.g., mangiferin, curcumin, resveratrol) for targeted release in pancreatic islets or atherosclerotic plaques (Geraskevich et al., 2024)

First comes inflammation , with platelet activation and release of growth factors

Additional well-conducted and well-reported studies are needed, accompanied by the use of accepted definitions and causality assessment tools to address the lack of published literature regarding this issue

The needles used for administration are insulin style, which are very small and thin