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Improvement in fibrosis by 1 stage, without worsening of steatohepatitis, occurred in approximately one-third of semaglutide-treated patients, compared with approximately one-fifth of those receiving placebo, corresponding to an absolute difference of 12-15 percentage points and an NNT of ~6-8
Patients in large clinical trials for GLP-1s lost an average of 15% to 20% of their body weight, depending on the drug they were given
Tripathi MK, Kartawy M, Amal H
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