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Common Mild Side Effects Short-term redness or slight irritation at the injection site Light water retention, especially during the initial weeks Increased appetite Mild headaches (rare and usually transient) Temporary fatigue or lightheadedness immediately after injection Who Should Avoid This Therapy People with an active cancer diagnosis or history of cancer, as GH secretagogues increase cellular replication rates Pregnant or breastfeeding individuals should avoid this therapy due to insufficient safety data on its effects during these stages
CJC-1295 DAC extends the GH release window from minutes to hours through its Drug Affinity Complex, which binds to albumin and prolongs half-life to 6-8 days (Teichman et al., J Clin Endocrinol Metab, 2006)
Not evaluated by the MHRA or FDA
FDA-approved small molecule drugs with covalent mechanisms of action
