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Notably, SCD endures overwhelming oxidative stress and consumes significant amounts of cysteine for glutathione (GSH) synthesis

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In most cases, patients can continue to take the drugs, however, individual risk factors for complications should be assessed prior to surgery before moving forward. The authors wrote, the purpose of this clinical practice guide is to offer unified, multi-society guidance for safely managing patients needing GLP-1RA therapy regardless of indication, which currently includes type 2 diabetes, overweight and obesity, and heart failure, during the periprocedural period. Full guidance is published in SOARD , Clinical Gastroenterology and Hepatology and Surgical Endoscopy.

Sanders MH, Givelber R