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Description

Local generation of fumarate promotes DNA repair through inhibition of histone H3 demethylation

Reviewed by

Vecchia DD, Kanazawa LKS, Wendler E, Hocayen PdAS, Vital MABF, Takahashi RN, et al

Conclusions To summarize, the 68-week treatment with coadministered cagrilintide and semaglutide resulted in substantial and clinically meaningful weight loss in adults with overweight or obesity, significantly outperforming monotherapies and placebo (- 5.5% vs

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