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UK standard treatment regimens (per BNF and NHS guidance): Dietary deficiency (e.g., in vegans): oral cyanocobalamin 50150 micrograms daily between meals Pernicious anaemia or other absorption-related deficiency : intramuscular hydroxocobalamin 1 mg on alternate days for two weeks (loading), then 1 mg every two to three months as maintenance

But these doses are likely too small to provide any significant impact

For moderate weight loss in the 30 to 70 pound range, many people find that GHK-Cu reduces laxity enough that surgery becomes unnecessary

Although retatrutide is not yet available outside of clinical trials, the factors that influence starting dose and titration speed are broadly consistent with those applied to similar licensed medicines